I'm using a Pedaltrain Metro 16 pedalboard, so space is limited (by choice – I like keeping things a bit minimal). At first, I was using Sommer Cable Spirit XS cables (also very high quality), but found it a challenge to fit all pedals I wanted on my board.
I first heard about the Evidence Audio SIS system on That Pedal Show. I decided to make the investment so I could clean up my pedal board and perhaps fit one extra pedal. I regret not buying into this system from the very start. The angled SIS plugs are much more compact than the Hicon plugs on the Spirit XS, allowing pedals to be placed much closer to each other. As a result, I'm able to fit seven pedals on my Metro 16 (with room for one more - yay!). For a photo of my upgraded board, visit: yfoto [dot] nl [slash] sis
The sound quality of the SIS cables is excellent. I could swear I hear a bit more high end than with the Spirit XS cables, but given I paid about double the price to connect my seven pedals, it could just be a psychological thing. ;-)
Fitting the SIS jacks onto the cable took me a bit of practice at first, but after the first one, the others were easy.
If you just have two or three loose pedals on the floor, this will be overkill. For everyone else, this is the best choice of patch cable for your pedalboard, period.