Nothing in this world is made to last forever. This is also true for pots, unfortunately, and thus there will come the day when your pot will no longer do its job to your full satisfaction. There are two fundamental causes for such faults:
Due to the movement of the wiper against the resistive element, the problem may be wear on one or both of the components. This causes contact problems mostly. The consequences may vary and depend mostly on how the pot is applied.
When stationary, i.e. not being turned, the problem will most likely not be noticeable. When changing the volume or fading, there can be "dead spots" when the shaft is turned. Scratchy or crackling sounds my occur. For such potentiometers, there is no hope - they have reached the end of their useful lives, and the only thing you can do is get a replacement.
The second source of faults is dirt. Most pots on an e-guitar are not completely enclosed. Usually, the casing has a lid where the contacts are, so that dirt can enter and then settle on the resistive element. This also leads to problems with the electric contact.
This problem can be recognised from the slight scratching noise that arises when the shaft is turned. Turning the pot knob to and fro a couple of times should suffice to alleviate the problem. In doing so, you basically move the dirt aside. If this doesn't help, you can resort to a chemical cleaning spray designed for electric contacts. They dissolve the dirt on the surface and then wash it away (a proven cleaner is CaiLube MCL Spray, for example). But most cleaners leave their own traces, so that this solution normally is only a short-term fix!
To do it right, the pot is opened and all contacts and the resistive element are cleaned with isopropyl alcohol. After this procedure a potentiometer can definitely awake to renewed life. It is definitely worth giving a try on expensive special potentiometers.
As a rule, however, interference caused by dirt goes hand in hand with increasing wear and tear. So it is safe to say that a scratchy or crackling pot will need replacing fairly soon.
Before embarking on buying a new potentiometer to replace a faulty one, make sure you know a couple of things: