Starting from the cons, the most relevant problem I encountered is with the USB connection, the input of the TASCAM is rather mobile and in some dispositions this might cause the audio interface to disconnect (at a risk of ear damage). I think an L-shaped USB cable might help a lot. Secondarily, the TASCAM has some really great in-built reverbs, but it’s still a mystery why these are not straightforwardly recorded when activated - it seems like a re-routing, at a cost of an additional input, is necessary!
Main pro in my opinion is the quality of the preamps, I don’t feel the need of any additional hardware and, when feasible, turning the gain up always sound clear and musical. Nothing more to say!