I use VEP to host a few instances of Omnispheres, because in my huge Cubase template (3000+ tracks, all disabled) they simply take too much time to load sounds. So I link a VEP project to a Cubase Project, and all my CPU-hungry plugins are extremely fast since they are not loaded directly in Cubase anymore. When I close my Cubase project and re-open it, VEP reload automatically all my plugins linked to that Cubase project with the right settings, patches I created/modified, ...
It's not cheap, but it works very well. You can search on Google many ways to use it. My use of it is pretty basic, but a lot of film composers use it with slave computers in order to load massive templates without having to reload samples every time they open a new project in their DAW.